combining treatment as usual and experimental placebo control groups in one meta analysis

[michelle richardson]

 

Hi all,

 

I'm conducting a sr and meta analysis of interventions that target children with ADHD in school settings.  The studies reviewed include both treatment as usual comparisons and experiments placebo controls.  Can these types of studies be combined in a single meta analytic synthesis?  I wondered about conducting a moderator analysis using design type as a predictor variable?

Any comments welcome!

 

thanks,

 

Michelle

[David Finitsis]

As long as both types of studies use the same two-group design, my understanding is that you could combine them.  It sounds like you anticipate heterogeneity of effect size from this a priori so random effects assumptions would be indicated and conducting a moderator analysis with design type as your moderator also makes good sense.  Happy meta-analyzing!

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