Tools for Those Who Summarize the Evidence Base
Reverberations continue to be felt as a result of the meta-analysis by Kirsch et al. (2008) on the efficacy of antidepressants. This article in Psychiatric Times online reacts to the implications and offers an alternative interpretation using a different meta.
And here ( Leucht%20et%20al.%202012.pdf ) is the meta that the authors argue from. It's actually a meta of metas. What is that called? A Meta-meta? An Uber-meta? A Macro-meta?
It stands out to even the casual reader that the Leucht and Kirsch metas are asking somewhat related but very different questions. The article strikes me as reactionary and points out how meta-analysis, as a tool, can be used both in the service of shifting paradigms and in resisting that same shift.